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A new humanized in vivo model of KIT D816V(+) advanced systemic mastocytosis monitored using a secreted luciferase

Systemic mastocytosis are rare neoplasms characterized by accumulation of mast cells in at least one internal organ. The majority of systemic mastocytosis patients carry KIT D816V mutation, which activates constitutively the KIT receptor. Patient with advanced forms of systemic mastocytosis, such as...

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Detalles Bibliográficos
Autores principales: Bibi, Siham, Zhang, Yanyan, Hugonin, Caroline, Mangean, Mallorie Depond, He, Liang, Wedeh, Ghaith, Launay, Jean-Marie, Van Rijn, Sjoerd, Würdinger, Thomas, Louache, Fawzia, Arock, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347747/
https://www.ncbi.nlm.nih.gov/pubmed/27783996
http://dx.doi.org/10.18632/oncotarget.12824