A fully human anti-CD47 blocking antibody with therapeutic potential for cancer

CD47/SIRPα interaction serves as an immune checkpoint for macrophage-mediated phagocytosis. Mouse anti-CD47 blocking antibodies had demonstrated potent efficacy in the treatment of both leukemic and solid tumors in preclinical experimentations, and therefore had moved forward rapidly into clinical t...

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Detalles Bibliográficos
Autores principales: Zeng, Dadi, Sun, Qiang, Chen, Ang, Fan, Jiangfeng, Yang, Xiaopeng, Xu, Lei, Du, Peng, Qiu, Weiyi, Zhang, Weicai, Wang, Shuang, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347751/
https://www.ncbi.nlm.nih.gov/pubmed/27863402
http://dx.doi.org/10.18632/oncotarget.13349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347751/
https://www.ncbi.nlm.nih.gov/pubmed/27863402
http://dx.doi.org/10.18632/oncotarget.13349

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