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Targeted ultra-deep sequencing unveils a lack of driver-gene mutations linking non-hereditary gastrointestinal stromal tumors and highly prevalent second primary malignancies: random or nonrandom, that is the question

The association of non-hereditary (sporadic) gastrointestinal stromal tumors (GISTs) and second primary malignancies is known to be nonrandom, although the underlying molecular mechanisms remain unknown. In this study, 136 of 749 (18.1%) patients with sporadic GISTs were found to have additional ass...

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Detalles Bibliográficos
Autores principales: Lai, Bo-Ru, Wu, Yu-Tung, Kuo, Yung-Chia, Hsu, Hung-Chih, Chen, Jen-Shi, Chen, Tse-Ching, Wu, Ren-Chin, Chiu, Cheng-Tang, Yeh, Chun-Nan, Yeh, Ta-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347768/
https://www.ncbi.nlm.nih.gov/pubmed/27806309
http://dx.doi.org/10.18632/oncotarget.12452