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Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis

There is currently a paucity of preclinical models available to study the metastatic process in esophageal cancer. Here we report FLO-1, and its isogenic derivative FLO-1(LM), as two spontaneously metastatic cell line models of human esophageal adenocarcinoma. We show that FLO-1 has undergone epithe...

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Detalles Bibliográficos
Autores principales: Liu, David S., Hoefnagel, Sanne J.M., Fisher, Oliver M., Krishnadath, Kausilia K., Montgomery, Karen G., Busuttil, Rita A., Colebatch, Andrew J., Read, Matthew, Duong, Cuong P., Phillips, Wayne A., Clemons, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347774/
https://www.ncbi.nlm.nih.gov/pubmed/27863424
http://dx.doi.org/10.18632/oncotarget.13391