Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice

Peptide hormone-based targeted therapy to tumors has been studied extensively. Our previous study shows that somatostatin receptor expresses high level on drug-resistant human ovarian cancer. The paclitaxel-octreotide conjugate (POC) exhibits enhanced growth inhibition, as well as reduced toxicity,...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Zhang, Xiao-Yu, Shen, Yang, Fan, Li-Li, Ren, Mu-Lan, Wu, Yong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347781/
https://www.ncbi.nlm.nih.gov/pubmed/27825139
http://dx.doi.org/10.18632/oncotarget.13120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347781/
https://www.ncbi.nlm.nih.gov/pubmed/27825139
http://dx.doi.org/10.18632/oncotarget.13120

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