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Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice

Peptide hormone-based targeted therapy to tumors has been studied extensively. Our previous study shows that somatostatin receptor expresses high level on drug-resistant human ovarian cancer. The paclitaxel-octreotide conjugate (POC) exhibits enhanced growth inhibition, as well as reduced toxicity,...

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Detalles Bibliográficos
Autores principales:	Chen, Xi, Zhang, Xiao-Yu, Shen, Yang, Fan, Li-Li, Ren, Mu-Lan, Wu, Yong-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347781/ https://www.ncbi.nlm.nih.gov/pubmed/27825139 http://dx.doi.org/10.18632/oncotarget.13120

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