A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

Chondrosarcoma is one of the bone tumor with high mortality in respond to poor radiation and chemotherapy treatment. Here, we analyze the antitumor activity of a novel benzofuran derivative, 2-amino-3-(2-chlorophenyl)-6-(4-dimethylaminophenyl)benzofuran-4-yl acetate (ACDB), in human chondrosarcoma c...

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Detalles Bibliográficos
Autores principales: Su, Chen-Ming, Chen, Chien-Yu, Lu, Tingting, Sun, Yi, Li, Weimin, Huang, Yuan-Li, Tsai, Chun-Hao, Chang, Chih-Shiang, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347786/
https://www.ncbi.nlm.nih.gov/pubmed/27835579
http://dx.doi.org/10.18632/oncotarget.13171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347786/
https://www.ncbi.nlm.nih.gov/pubmed/27835579
http://dx.doi.org/10.18632/oncotarget.13171

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