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TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon

BACKGROUND: Toll-interacting protein is a negative regulator in the TLR signaling cascade, particularly by impeding the TLR2 and, TLR4 pathway. Recently, TOLLIP was shown to regulate human TLR signaling pathways. Two common TOLLIP polymorphisms (rs5743899 and rs3750920) were reported to be influenci...

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Detalles Bibliográficos
Autores principales: Brasil, Larissa W., Barbosa, Laila R. A., de Araujo, Felipe J., da Costa, Allyson G., da Silva, Luan D. O., Pinheiro, Suzana K., de Almeida, Anne C. G., Kuhn, Andrea, Vitor-Silva, Sheila, de Melo, Gisely C., Monteiro, Wuelton M., de Lacerda, Marcus V. G., Ramasawmy, Rajendranath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347824/
https://www.ncbi.nlm.nih.gov/pubmed/28288644
http://dx.doi.org/10.1186/s12936-017-1754-7