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Meta‐analysis of few small studies in orphan diseases

Meta‐analyses in orphan diseases and small populations generally face particular problems, including small numbers of studies, small study sizes and heterogeneity of results. However, the heterogeneity is difficult to estimate if only very few studies are included. Motivated by a systematic review i...

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Detalles Bibliográficos
Autores principales: Friede, Tim, Röver, Christian, Wandel, Simon, Neuenschwander, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347842/
https://www.ncbi.nlm.nih.gov/pubmed/27362487
http://dx.doi.org/10.1002/jrsm.1217