Stereoselective Synthesis of Functionalized Bicyclic Scaffolds by Passerini 3‐Center‐2‐Component Reactions of Cyclic Ketoacids

We report the use of bifunctional starting materials (ketoacids) in a diastereoselective Passerini three‐center‐two‐component reaction. Study of the reaction scope revealed the required structural features for stereoselectivity in the isocyanide addition. In this system, an interesting isomerization...

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Detalles Bibliográficos
Autores principales: Cioc, Răzvan C., Estévez, Verónica, van der Niet, Daan J., Vande Velde, Christophe M. L., Turrini, Nikolaus G., Hall, Mélanie, Faber, Kurt, Ruijter, Eelco, Orru, Romano V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347843/
https://www.ncbi.nlm.nih.gov/pubmed/28344504
http://dx.doi.org/10.1002/ejoc.201601432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347843/
https://www.ncbi.nlm.nih.gov/pubmed/28344504
http://dx.doi.org/10.1002/ejoc.201601432

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