Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets

ESSENTIALS: Dimeric high‐affinity collagen receptor glycoprotein VI (GPVI) is present on resting platelets. Spatio‐temporal organization of platelet GPVI‐dimers was evaluated using advanced microscopy. Upon platelet adhesion to collagenous substrates, GPVI‐dimers coalesce to form clusters. Clusterin...

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Detalles Bibliográficos
Autores principales: Poulter, N. S., Pollitt, A. Y., Owen, D. M., Gardiner, E. E., Andrews, R. K., Shimizu, H., Ishikawa, D., Bihan, D., Farndale, R. W., Moroi, M., Watson, S. P., Jung, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347898/
https://www.ncbi.nlm.nih.gov/pubmed/28058806
http://dx.doi.org/10.1111/jth.13613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347898/
https://www.ncbi.nlm.nih.gov/pubmed/28058806
http://dx.doi.org/10.1111/jth.13613

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