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Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest‐like precursors

In this study, we propose a novel method for inducing neuronal cells by briefly exposing them to small‐molecule cocktails in a step‐by‐step manner. Global gene expression analysis with immunohistochemical staining and calcium flux assays reveal the generation of neurons from mouse embryonic fibrobla...

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Detalles Bibliográficos
Autores principales: Takayama, Yuzo, Wakabayashi, Tamami, Kushige, Hiroko, Saito, Yutaka, Shibuya, Yoichiro, Shibata, Shinsuke, Akamatsu, Wado, Okano, Hideyuki, Kida, Yasuyuki S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347899/
https://www.ncbi.nlm.nih.gov/pubmed/28129669
http://dx.doi.org/10.1002/1873-3468.12572