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Use of high‐frequency ultrasound to study the prenatal development of cranial neural tube defects and hydrocephalus in Gldc‐deficient mice

OBJECTIVE: We used non‐invasive high‐frequency ultrasound (HFUS) imaging to investigate embryonic brain development in a mouse model for neural tube defects (NTDs) and non‐ketotic hyperglycinemia (NKH). METHOD: Using HFUS, we imaged embryos carrying loss of function alleles of Gldc encoding glycine...

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Detalles Bibliográficos
Autores principales: Autuori, Maria C., Pai, Yun J., Stuckey, Daniel J., Savery, Dawn, Marconi, Anna M., Massa, Valentina, Lythgoe, Mark F., Copp, Andrew J., David, Anna L., Greene, Nicholas D.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347903/
https://www.ncbi.nlm.nih.gov/pubmed/28056489
http://dx.doi.org/10.1002/pd.5004