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Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
Polymorphic variants of the FTO (fat mass and obesity) gene associate with body mass index in humans, but the underlying molecular mechanisms have not been firmly determined. FTO is linked to energy homeostasis via amino acid sensing and is thought to activate the mammalian target of rapamycin compl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347998/ https://www.ncbi.nlm.nih.gov/pubmed/28288181 http://dx.doi.org/10.1371/journal.pone.0168182 |