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Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy

Polymorphic variants of the FTO (fat mass and obesity) gene associate with body mass index in humans, but the underlying molecular mechanisms have not been firmly determined. FTO is linked to energy homeostasis via amino acid sensing and is thought to activate the mammalian target of rapamycin compl...

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Detalles Bibliográficos
Autores principales: Aas, Aleksander, Isakson, Pauline, Bindesbøll, Christian, Alemu, Endalkachew A., Klungland, Arne, Simonsen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347998/
https://www.ncbi.nlm.nih.gov/pubmed/28288181
http://dx.doi.org/10.1371/journal.pone.0168182

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