Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies

BACKGROUND: A number of transporter proteins are expressed in the placenta, and they facilitate the placental transfer of drugs. The inhibition of P-glycoprotein (P-gp) was previously found to be associated with an increase in the risk of congenital anomalies caused by drug substrates of this transp...

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Detalles Bibliográficos
Autores principales: Daud, Aizati N. A., Bergman, Jorieke E. H., Oktora, Monika P., Kerstjens-Frederikse, Wilhelmina S., Groen, Henk, Bos, Jens H., Hak, Eelko, Wilffert, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348032/
https://www.ncbi.nlm.nih.gov/pubmed/28288183
http://dx.doi.org/10.1371/journal.pone.0173530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348032/
https://www.ncbi.nlm.nih.gov/pubmed/28288183
http://dx.doi.org/10.1371/journal.pone.0173530

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