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Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells

Trials to reintroduce chloroquine into regions of Africa where P. falciparum has regained susceptibility to chloroquine are underway. However, there are long-standing concerns about whether chloroquine increases lytic-replication of Epstein-Barr virus (EBV), thereby contributing to the development o...

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Detalles Bibliográficos
Autores principales: Li, Xiaofan, Burton, Eric M., Bhaduri-McIntosh, Sumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348047/
https://www.ncbi.nlm.nih.gov/pubmed/28249048
http://dx.doi.org/10.1371/journal.ppat.1006249