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Differential Sensitivity of Target Genes to Translational Repression by miR-17~92

MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of hundreds of target genes and each to a small degree, but it remains unclear how small changes in hundreds of target genes are translated into the specific function of a miRNA. Here, we conducted an integrated ana...

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Detalles Bibliográficos
Autores principales: Jin, Hyun Yong, Oda, Hiroyo, Chen, Pengda, Yang, Chao, Zhou, Xiaojuan, Kang, Seung Goo, Valentine, Elizabeth, Kefauver, Jennifer M., Liao, Lujian, Zhang, Yaoyang, Gonzalez-Martin, Alicia, Shepherd, Jovan, Morgan, Gareth J., Mondala, Tony S., Head, Steven R., Kim, Pyeung-Hyeun, Xiao, Nengming, Fu, Guo, Liu, Wen-Hsien, Han, Jiahuai, Williamson, James R., Xiao, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348049/
https://www.ncbi.nlm.nih.gov/pubmed/28241004
http://dx.doi.org/10.1371/journal.pgen.1006623