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Differential Sensitivity of Target Genes to Translational Repression by miR-17~92
MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of hundreds of target genes and each to a small degree, but it remains unclear how small changes in hundreds of target genes are translated into the specific function of a miRNA. Here, we conducted an integrated ana...
Autores principales: | Jin, Hyun Yong, Oda, Hiroyo, Chen, Pengda, Yang, Chao, Zhou, Xiaojuan, Kang, Seung Goo, Valentine, Elizabeth, Kefauver, Jennifer M., Liao, Lujian, Zhang, Yaoyang, Gonzalez-Martin, Alicia, Shepherd, Jovan, Morgan, Gareth J., Mondala, Tony S., Head, Steven R., Kim, Pyeung-Hyeun, Xiao, Nengming, Fu, Guo, Liu, Wen-Hsien, Han, Jiahuai, Williamson, James R., Xiao, Changchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348049/ https://www.ncbi.nlm.nih.gov/pubmed/28241004 http://dx.doi.org/10.1371/journal.pgen.1006623 |
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