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Mechanism of Shiga Toxin Clustering on Membranes

[Image: see text] The bacterial Shiga toxin interacts with its cellular receptor, the glycosphingolipid globotriaosylceramide (Gb3 or CD77), as a first step to entering target cells. Previous studies have shown that toxin molecules cluster on the plasma membrane, despite the apparent lack of direct...

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Detalles Bibliográficos
Autores principales: Pezeshkian, Weria, Gao, Haifei, Arumugam, Senthil, Becken, Ulrike, Bassereau, Patricia, Florent, Jean-Claude, Ipsen, John Hjort, Johannes, Ludger, Shillcock, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348102/
https://www.ncbi.nlm.nih.gov/pubmed/27943675
http://dx.doi.org/10.1021/acsnano.6b05706