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Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice
Serotonin (5-HT) and brain derived neurotrophic factor (BDNF) are two signaling molecules that play important regulatory roles in the development and plasticity of neural circuits that are known to be altered in depression. However, the mechanism by which 5-HT regulates BDNF signaling is unknown. In...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348279/ https://www.ncbi.nlm.nih.gov/pubmed/27620841 http://dx.doi.org/10.1038/mp.2016.145 |