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Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice

Serotonin (5-HT) and brain derived neurotrophic factor (BDNF) are two signaling molecules that play important regulatory roles in the development and plasticity of neural circuits that are known to be altered in depression. However, the mechanism by which 5-HT regulates BDNF signaling is unknown. In...

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Detalles Bibliográficos
Autores principales: Pandya, Chirayu D, Hoda, Nasrul, Crider, Amanda, Peter, Diya, Kutiyanawalla, Ammar, Kumar, Sanjiv, Ahmed, Anthony O, Turecki, Gustavo, Hernandez, Caterina M, Terry, Alvin V, Pillai, Anilkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348279/
https://www.ncbi.nlm.nih.gov/pubmed/27620841
http://dx.doi.org/10.1038/mp.2016.145