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Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

In this study, we attempted to explore the effect and possible mechanism of Andrographolide on OVA-induced asthma. OVA challenge induced significant airway inflammatory cell recruitment and lung histological alterations, which were ameliorated by Andrographolide. The protein levels of cytokines in b...

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Detalles Bibliográficos
Autores principales: Peng, Shuang, Gao, Jian, Liu, Wen, Jiang, Chunhong, Yang, Xiaoling, Sun, Yang, Guo, Wenjie, Xu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348318/
https://www.ncbi.nlm.nih.gov/pubmed/27793052
http://dx.doi.org/10.18632/oncotarget.12918