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Strategies for power calculations in predictive biomarker studies in survival data

PURPOSE: Biomarkers and genomic signatures represent potentially predictive tools for precision medicine. Validation of predictive biomarkers in prospective or retrospective studies requires statistical justification of power and sample size. However, the design of these studies is complex and the s...

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Detalles Bibliográficos
Autores principales: Chen, Dung-Tsa, Huang, Po-Yu, Lin, Hui-Yi, Haura, Eric B., Antonia, Scott J., Cress, W. Douglas, Gray, Jhanelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348326/
https://www.ncbi.nlm.nih.gov/pubmed/27661007
http://dx.doi.org/10.18632/oncotarget.12124