S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite

Arsenic, a widely distributed carcinogen, is known to significantly amplify the impact of other carcinogens through inhibition of DNA repair. Our recent work suggests that reactive oxygen/nitrogen species (ROS/RNS) induced by arsenite (AsIII) play an important role in the inhibition of the DNA repai...

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Detalles Bibliográficos
Autores principales: Zhou, Xixi, Cooper, Karen L., Huestis, Juliana, Xu, Huan, Burchiel, Scott W., Hudson, Laurie G., Liu, Ke Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348335/
https://www.ncbi.nlm.nih.gov/pubmed/27741521
http://dx.doi.org/10.18632/oncotarget.12613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348335/
https://www.ncbi.nlm.nih.gov/pubmed/27741521
http://dx.doi.org/10.18632/oncotarget.12613

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