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S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite
Arsenic, a widely distributed carcinogen, is known to significantly amplify the impact of other carcinogens through inhibition of DNA repair. Our recent work suggests that reactive oxygen/nitrogen species (ROS/RNS) induced by arsenite (AsIII) play an important role in the inhibition of the DNA repai...
Autores principales: | Zhou, Xixi, Cooper, Karen L., Huestis, Juliana, Xu, Huan, Burchiel, Scott W., Hudson, Laurie G., Liu, Ke Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348335/ https://www.ncbi.nlm.nih.gov/pubmed/27741521 http://dx.doi.org/10.18632/oncotarget.12613 |
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