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TRPC1-STIM1 activation modulates transforming growth factor β-induced epithelial-to-mesenchymal transition

Activation of Epithelial-to-Mesenchymal Transition (EMT) is important for tumor metastasis. Although growth factors such as TGFβ and EGF have been shown to induce EMT in breast epithelial cells, the mechanism resulting in migration is not well understood. Herein, we provide evidence that Ca(2+) entr...

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Detalles Bibliográficos
Autores principales: Schaar, Anne, Sukumaran, Pramod, Sun, Yuyang, Dhasarathy, Archana, Singh, Brij B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348340/
https://www.ncbi.nlm.nih.gov/pubmed/27793015
http://dx.doi.org/10.18632/oncotarget.12895