Cargando…
TRPC1-STIM1 activation modulates transforming growth factor β-induced epithelial-to-mesenchymal transition
Activation of Epithelial-to-Mesenchymal Transition (EMT) is important for tumor metastasis. Although growth factors such as TGFβ and EGF have been shown to induce EMT in breast epithelial cells, the mechanism resulting in migration is not well understood. Herein, we provide evidence that Ca(2+) entr...
Autores principales: | Schaar, Anne, Sukumaran, Pramod, Sun, Yuyang, Dhasarathy, Archana, Singh, Brij B |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348340/ https://www.ncbi.nlm.nih.gov/pubmed/27793015 http://dx.doi.org/10.18632/oncotarget.12895 |
Ejemplares similares
-
TGFβ‐induced epithelial‐to‐mesenchymal transition in prostate cancer cells is mediated via TRPM7 expression
por: Sun, Yuyang, et al.
Publicado: (2018) -
The calcium channel proteins ORAI3 and STIM1 mediate TGF-β induced Snai1 expression
por: Bhattacharya, Atrayee, et al.
Publicado: (2018) -
Ca(2+) entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex
por: Schaar, Anne, et al.
Publicado: (2019) -
The TRPC1 Ca(2+)-permeable channel inhibits exercise-induced protection against high-fat diet-induced obesity and type II diabetes
por: Krout, Danielle, et al.
Publicado: (2017) -
TRPC1 expression and function inhibit ER stress and cell death in salivary gland cells
por: Sukumaran, Pramod, et al.
Publicado: (2018)