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Metformin enhances the radiosensitivity of human liver cancer cells to γ–rays and carbon ion beams

The purpose of this study was to investigate the effect of metformin on the responses of hepatocellular carcinoma (HCC) cells to γ–rays (low-linear energy transfer (LET) radiation) and carbon-ion beams (high-LET radiation). HCC cells were pretreated with metformin and exposed to a single dose of γ–r...

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Detalles Bibliográficos
Autores principales: Kim, Eun Ho, Kim, Mi-Sook, Furusawa, Yoshiya, Uzawa, Akiko, Han, Soorim, Jung, Won-Gyun, Sai, Sei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348341/
https://www.ncbi.nlm.nih.gov/pubmed/27802188
http://dx.doi.org/10.18632/oncotarget.12966