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Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression

Lipid metabolism is crucially involved with the promotion of malignant progression and metastasis in various cancers. Growing evidence suggests that many types of cancers express high levels of sphingosine kinase 1 (Sphk1), which is known to mediate cell proliferation We hypothesized that Sphk1/sphi...

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Detalles Bibliográficos
Autores principales: Li, Shifei, Zhou, Yan, Zheng, Xiaodong, Wu, Xiujuan, Liang, Yueyang, Wang, Shushu, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348342/
https://www.ncbi.nlm.nih.gov/pubmed/27811358
http://dx.doi.org/10.18632/oncotarget.13013