Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma

The hexosamine biosynthetic pathway (HBP) requires two key nutrients glucose and glutamine for O-linked N-acetylglucosamine (O-GlcNAc) cycling, a post-translational protein modification that adds GlcNAc to nuclear and cytoplasmic proteins. Increased GlcNAc has been linked to regulatory factors invol...

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Detalles Bibliográficos
Autores principales: Pham, Lan V., Bryant, Jerry L., Mendez, Richard, Chen, Juan, Tamayo, Archito T., Xu, Zijun Y., Young, Ken H., Manyam, Ganiraju C., Yang, David, Medeiros, L. Jeffrey, Ford, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348344/
https://www.ncbi.nlm.nih.gov/pubmed/27716624
http://dx.doi.org/10.18632/oncotarget.12413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348344/
https://www.ncbi.nlm.nih.gov/pubmed/27716624
http://dx.doi.org/10.18632/oncotarget.12413

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