Cargando…
Hmgb1 inhibits Klotho expression and malignant phenotype in melanoma cells by activating NF-κB
The molecular and cellular mechanisms behind the involvement of inflammation in melanoma have not been fully elucidated. In this study, knockdown of Hmgb1 expression increased apoptosis, reduced invasion and p-NF-κB expression, but increased Klotho protein level in melanoma tumor cells. The effect o...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348353/ https://www.ncbi.nlm.nih.gov/pubmed/27779100 http://dx.doi.org/10.18632/oncotarget.12623 |