PC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity

The androgen receptor (AR) is not only a ligand-dependent transcription factor, but also functions as a licensing factor, a component of DNA replication, which is degraded during mitosis. Furthermore, the deregulation of AR activity is involved in the initiation of prostate cancer and contributes to...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Zhang, Hui, Zhang, Xiaoqing, Wang, Peng, Wang, Hongtao, Huang, Fang, Zhou, Chenyan, Zhou, Jianguang, Li, Shanhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348399/
https://www.ncbi.nlm.nih.gov/pubmed/27835608
http://dx.doi.org/10.18632/oncotarget.13230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348399/
https://www.ncbi.nlm.nih.gov/pubmed/27835608
http://dx.doi.org/10.18632/oncotarget.13230

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