Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy

Recent reports suggest that colorectal carcinoma (CRC) may be sustained by a small subpopulation of cells, termed cancer stem cells (CSCs), which have drug resistance properties as a key reason for chemotherapy failure. The epidermal growth factor receptor (EGFR) controls CRC initiation and progress...

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Detalles Bibliográficos
Autores principales: Feng, Ye, Gao, Shuohui, Gao, Yongjian, Wang, Xuefeng, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348401/
https://www.ncbi.nlm.nih.gov/pubmed/27833077
http://dx.doi.org/10.18632/oncotarget.13233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348401/
https://www.ncbi.nlm.nih.gov/pubmed/27833077
http://dx.doi.org/10.18632/oncotarget.13233

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