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AEG-1 knockdown in colon cancer cell lines inhibits radiation-enhanced migration and invasion in vitro and in a novel in vivo zebrafish model

BACKGROUND: Radiotherapy is a well-established anti-cancer treatment. Although radiotherapy has been shown to significantly decrease the local relapse in rectal cancer patients, the rate of distant metastasis is still very high. The aim of this study was to evaluate whether AEG-1 is involved in radi...

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Detalles Bibliográficos
Autores principales: Gnosa, Sebastian, Capodanno, Alessandra, Murthy, Raghavendra Vasudeva, Ejby Jensen, Lasse Dahl, Sun, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348418/
https://www.ncbi.nlm.nih.gov/pubmed/27835571
http://dx.doi.org/10.18632/oncotarget.13155