Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells

Similar to Drosophila Sprouty (SPRY), mammalian SPRY proteins inhibit the receptor tyrosine kinase-mediated activation of cellular signaling pathways. SPRY2 expression levels have been shown to be down-regulated in human ovarian cancer, and patients with low SPRY2 expression have significantly poore...

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Detalles Bibliográficos
Autores principales: Cheng, Jung-Chien, Chang, Hsun-Ming, Xiong, Siyuan, So, Wai-Kin, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348419/
https://www.ncbi.nlm.nih.gov/pubmed/27835572
http://dx.doi.org/10.18632/oncotarget.13162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348419/
https://www.ncbi.nlm.nih.gov/pubmed/27835572
http://dx.doi.org/10.18632/oncotarget.13162

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