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Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells

Similar to Drosophila Sprouty (SPRY), mammalian SPRY proteins inhibit the receptor tyrosine kinase-mediated activation of cellular signaling pathways. SPRY2 expression levels have been shown to be down-regulated in human ovarian cancer, and patients with low SPRY2 expression have significantly poore...

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Detalles Bibliográficos
Autores principales:	Cheng, Jung-Chien, Chang, Hsun-Ming, Xiong, Siyuan, So, Wai-Kin, Leung, Peter C. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348419/ https://www.ncbi.nlm.nih.gov/pubmed/27835572 http://dx.doi.org/10.18632/oncotarget.13162

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