Integrated bioinformatics analysis of chromatin regulator EZH2 in regulating mRNA and lncRNA expression by ChIP sequencing and RNA sequencing

Enhancer of zeste homolog 2 (EZH2), a dynamic chromatin regulator in cancer, represents a potential therapeutic target showing early signs of promise in clinical trials. EZH2 ChIP sequencing data in 19 cell lines and RNA sequencing data in ten cancer types were downloaded from GEO and TCGA, respecti...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Luo, Mei, Shi, Xuejiao, Lu, Zhiliang, Sun, Shouguo, Huang, Jianbing, Chen, Zhaoli, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348424/
https://www.ncbi.nlm.nih.gov/pubmed/27835578
http://dx.doi.org/10.18632/oncotarget.13169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348424/
https://www.ncbi.nlm.nih.gov/pubmed/27835578
http://dx.doi.org/10.18632/oncotarget.13169

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