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Transcriptional repression of FOXO1 by KLF4 contributes to glioma progression

In this study, our findings indicated that FOXO1 expression frequently decreased in glioma tissues and cells. FOXO1 expression decrease correlated with glioma progression and predicted a worse overall survival of glioma patients. Restored FOXO1 expression inhibited glioma cells invasion and suppress...

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Detalles Bibliográficos
Autores principales: Tang, Guodong, Liu, Dingyang, Xiao, Gelei, Liu, Qing, Yuan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348427/
https://www.ncbi.nlm.nih.gov/pubmed/27835585
http://dx.doi.org/10.18632/oncotarget.13184