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The role of calpains in ventilator-induced diaphragm atrophy

BACKGROUND: Controlled mechanical ventilation (CMV) is associated with diaphragm dysfunction. Dysfunction results from muscle atrophy and injury of diaphragm muscle fibers. Enhanced proteolysis and reduced protein synthesis play an important role in the development of atrophy. The current study is t...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoping, van Hees, Hieronymus W. H., Heunks, Leo, Wang, Feifei, Shao, Lei, Huang, Jiaru, Shi, Lei, Ma, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348482/
https://www.ncbi.nlm.nih.gov/pubmed/28290154
http://dx.doi.org/10.1186/s40635-017-0127-4