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The role of calpains in ventilator-induced diaphragm atrophy
BACKGROUND: Controlled mechanical ventilation (CMV) is associated with diaphragm dysfunction. Dysfunction results from muscle atrophy and injury of diaphragm muscle fibers. Enhanced proteolysis and reduced protein synthesis play an important role in the development of atrophy. The current study is t...
Autores principales: | Zhu, Xiaoping, van Hees, Hieronymus W. H., Heunks, Leo, Wang, Feifei, Shao, Lei, Huang, Jiaru, Shi, Lei, Ma, Shaolin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348482/ https://www.ncbi.nlm.nih.gov/pubmed/28290154 http://dx.doi.org/10.1186/s40635-017-0127-4 |
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