Dickkopf-3 Upregulates VEGF in Cultured Human Endothelial Cells by Activating Activin Receptor-Like Kinase 1 (ALK1) Pathway

Dkk-3 is a member of the dickkopf protein family of secreted inhibitors of the Wnt pathway, which has been shown to enhance angiogenesis. The mechanism underlying this effect is currently unknown. Here, we used cultured HUVECs to study the involvement of the TGF-β and VEGF on the angiogenic effect o...

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Detalles Bibliográficos
Autores principales: Busceti, Carla L., Marchitti, Simona, Bianchi, Franca, Di Pietro, Paola, Riozzi, Barbara, Stanzione, Rosita, Cannella, Milena, Battaglia, Giuseppe, Bruno, Valeria, Volpe, Massimo, Fornai, Francesco, Nicoletti, Ferdinando, Rubattu, Speranza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348502/
https://www.ncbi.nlm.nih.gov/pubmed/28352232
http://dx.doi.org/10.3389/fphar.2017.00111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348502/
https://www.ncbi.nlm.nih.gov/pubmed/28352232
http://dx.doi.org/10.3389/fphar.2017.00111

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