Mitochondrial Dysfunction in the Pathogenesis of Rett Syndrome: Implications for Mitochondria-Targeted Therapies

First described over 50 years ago, Rett syndrome (RTT) is a neurodevelopmental disorder caused primarily by mutations of the X-linked MECP2 gene. RTT affects predominantly females, and has a prevalence of roughly 1 in every 10,000 female births. Prior to the discovery that mutations of MECP2 are the...

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Detalles Bibliográficos
Autores principales: Shulyakova, Natalya, Andreazza, Ana C., Mills, Linda R., Eubanks, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348512/
https://www.ncbi.nlm.nih.gov/pubmed/28352216
http://dx.doi.org/10.3389/fncel.2017.00058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348512/
https://www.ncbi.nlm.nih.gov/pubmed/28352216
http://dx.doi.org/10.3389/fncel.2017.00058

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