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DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling

Recent evidence from a comprehensive genome analysis and functional studies have revealed that FOXM1 is a crucial metastatic regulator that drives cancer progression. However, the regulatory mechanism by which FOXM1 exerts its metastatic functions in cancer cells remains obscure. Here, we report tha...

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Detalles Bibliográficos
Autores principales: Chan, D W, Hui, W W Y, Wang, J J, Yung, M M H, Hui, L M N, Qin, Y, Liang, R R, Leung, T H Y, Xu, D, Chan, K K L, Yao, K-M, Tsang, B K, Ngan, H Y S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348575/
https://www.ncbi.nlm.nih.gov/pubmed/27593933
http://dx.doi.org/10.1038/onc.2016.307