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Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upregulating Klotho
Cardiovascular diseases are common in patients with chronic kidney disease. One of the key symptoms is the calcification of the vascular smooth muscle cells (VSMCs), which is induced by dysregulated mineral metabolism with high circulating levels of inorganic phosphate (Pi) and calcium. Klotho, whic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348673/ https://www.ncbi.nlm.nih.gov/pubmed/28352317 http://dx.doi.org/10.3892/etm.2016.3996 |