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Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upregulating Klotho

Cardiovascular diseases are common in patients with chronic kidney disease. One of the key symptoms is the calcification of the vascular smooth muscle cells (VSMCs), which is induced by dysregulated mineral metabolism with high circulating levels of inorganic phosphate (Pi) and calcium. Klotho, whic...

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Detalles Bibliográficos
Autores principales: Cheng, Lijuan, Zhang, Lei, Yang, Jun, Hao, Lirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348673/
https://www.ncbi.nlm.nih.gov/pubmed/28352317
http://dx.doi.org/10.3892/etm.2016.3996