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Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions

BACKGROUND: Histone posttranslational modifications (PTMs) function to regulate chromatin structure and function in part through the recruitment of effector proteins that harbor specialized “reader” domains. Despite efforts to elucidate reader domain–PTM interactions, the influence of neighboring PT...

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Detalles Bibliográficos
Autores principales: Shanle, Erin K., Shinsky, Stephen A., Bridgers, Joseph B., Bae, Narkhyun, Sagum, Cari, Krajewski, Krzysztof, Rothbart, Scott B., Bedford, Mark T., Strahl, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348760/
https://www.ncbi.nlm.nih.gov/pubmed/28293301
http://dx.doi.org/10.1186/s13072-017-0117-5