Protein misfolding in neurodegenerative diseases: implications and strategies

A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic options are currently being explored that target different steps in the production and processing of proteins im...

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Detalles Bibliográficos
Autores principales: Sweeney, Patrick, Park, Hyunsun, Baumann, Marc, Dunlop, John, Frydman, Judith, Kopito, Ron, McCampbell, Alexander, Leblanc, Gabrielle, Venkateswaran, Anjli, Nurmi, Antti, Hodgson, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348787/
https://www.ncbi.nlm.nih.gov/pubmed/28293421
http://dx.doi.org/10.1186/s40035-017-0077-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348787/
https://www.ncbi.nlm.nih.gov/pubmed/28293421
http://dx.doi.org/10.1186/s40035-017-0077-5

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