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Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control

BACKGROUND: The G1-S phase transition is critical to maintaining proliferative control and preventing carcinogenesis. The retinoblastoma tumor suppressor is a key regulator of this step in the cell cycle. RESULTS: Here we use a structure–function approach to evaluate the contributions of multiple pr...

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Detalles Bibliográficos
Autores principales: Thwaites, Michael J., Cecchini, Matthew J., Talluri, Srikanth, Passos, Daniel T., Carnevale, Jasmyne, Dick, Frederick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348811/
https://www.ncbi.nlm.nih.gov/pubmed/28293272
http://dx.doi.org/10.1186/s13008-017-0029-6