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Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control

BACKGROUND: The G1-S phase transition is critical to maintaining proliferative control and preventing carcinogenesis. The retinoblastoma tumor suppressor is a key regulator of this step in the cell cycle. RESULTS: Here we use a structure–function approach to evaluate the contributions of multiple pr...

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Detalles Bibliográficos
Autores principales:	Thwaites, Michael J., Cecchini, Matthew J., Talluri, Srikanth, Passos, Daniel T., Carnevale, Jasmyne, Dick, Frederick A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348811/ https://www.ncbi.nlm.nih.gov/pubmed/28293272 http://dx.doi.org/10.1186/s13008-017-0029-6

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