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SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis

BACKGROUND: High levels of SOX2 protein are correlated with increased dissemination of breast cancer. However, the underlying molecular mechanisms are not fully understood. METHODS: In this study we investigate the role of SOX2 in breast cancer metastasis using multiple in vitro and in vivo assays i...

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Detalles Bibliográficos
Autores principales: Liu, Kuancan, Xie, Fuan, Gao, Anding, Zhang, Rui, Zhang, Long, Xiao, Zhangwu, Hu, Qiong, Huang, Weifeng, Huang, Qiaojia, Lin, Baoshun, Zhu, Jian, Wang, Haikun, Que, Jianwen, Lan, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348847/
https://www.ncbi.nlm.nih.gov/pubmed/28288641
http://dx.doi.org/10.1186/s12943-017-0632-9