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Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast
Impaired protein degradation and mitochondrial dysfunction are believed to contribute to neurodegenerative disorders, including Alzheimer disease (AD). In patients suffering from non-hereditary AD, UBB(+1), the frameshift variant of ubiquitin B, accumulated in neurons affected by neurofibrillary tan...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348975/ https://www.ncbi.nlm.nih.gov/pubmed/28357285 http://dx.doi.org/10.15698/mic2015.04.199 |